
Cancer-Related Pain: What It Means, What You Can Do, and Minimally Invasive Options
Cancer-related pain is more common than many people realize. Whether caused by the disease itself or the treatments used to fight it, this type of pain can impact mobility, sleep, and emotional well-being. The good news: today’s pain specialists have more tools than ever to diagnose the source of pain and create effective, individualized treatment plans—including many minimally invasive options that don’t require major surgery.
This guide breaks down what cancer-related pain means, what you can do to manage it, and how interventional pain medicine can help you reclaim comfort and quality of life.
What Cancer-Related Pain Really Means
Cancer pain varies widely depending on the type of cancer, its location, and its stage. Pain may be caused by:
- Tumor pressure on organs, bones, or nerves
- Bone metastases, which can weaken or fracture bones
- Treatment-related effects, such as surgery, chemotherapy, or radiation
- Post-surgical scar tissue, inflammation, or nerve irritation
- Peripheral neuropathy from chemotherapy
- Spasms or discomfort related to immobility or recovery
Pain may be constant or intermittent, sharp or aching, mild or severe. Regardless of the cause, no patient should feel they have to “push through” cancer pain. With the right plan, it is treatable.
What You Can Do Right Now
1. Keep a pain journal
Track when pain occurs, what it feels like, and what makes it worse or better. This helps your care team pinpoint the source.
2. Combine therapies when appropriate
Most patients see the best results with a multimodal approach, such as:
- Medications
- Physical or occupational therapy
- Mind-body practices
- Counseling or support groups
- Minimally invasive pain procedures
3. Stay ahead of the pain
Don’t wait for symptoms to escalate. Early intervention prevents the nervous system from becoming sensitized, which can make pain harder to manage later.
4. Work with a pain specialist
An interventional pain physician can identify whether your pain is due to nerves, joints, bones, or organs—and recommend targeted, evidence-based treatment.
Minimally Invasive Options for Cancer-Related Pain
Interventional pain medicine offers precise and effective treatments that help control pain without major surgery or heavy reliance on opioids.
1. Nerve Blocks
Targeted injections reduce pain signals from specific nerves or regions.
Options include:
- Intercostal nerve blocks (for chest and rib pain)
- Celiac plexus blocks (for abdominal cancers)
- Superior hypogastric plexus blocks (for pelvic pain)
- Lumbar sympathetic blocks (for neuropathic or vascular-related pain)
2. Radiofrequency Ablation (RFA)
RFA uses controlled heat to gently “quiet” overactive nerves transmitting pain. It is frequently used for:
- Abdominal or pelvic cancer pain
- Spine-related discomfort
- Pain from nerve compression
3. Vertebral Augmentation (Kyphoplasty or Vertebroplasty)
For patients with bone metastases or fractures causing spinal pain, these procedures stabilize the affected vertebrae—often providing rapid and lasting relief.
4. Intrathecal Pain Pumps
When pain is severe or widespread, a pain pump delivers medication directly to the spinal fluid, allowing for powerful relief with a fraction of the systemic dose. This can dramatically improve comfort and reduce side effects.
5. Spinal Cord Stimulation (SCS)
SCS interrupts pain signals before they reach the brain. For patients with neuropathic pain—from treatment or tumor-related nerve injury—it can restore function and reduce reliance on medications.
When to See a Pain Specialist
- Your pain is persistent or worsening
- Pain medications cause significant side effects
- Pain limits your mobility, sleep, or daily function
- You want options beyond traditional medication management
- You’re recovering from cancer but still experiencing chronic pain
Finding Relief Is Possible
Cancer-related pain is complex, but you don’t have to face it alone. With today’s minimally invasive treatments, many patients achieve meaningful, long-lasting relief—allowing them to focus on healing, connection, and quality of life.
If you or a loved one is experiencing cancer-related pain, a consultation with an interventional pain specialist can be a powerful step toward comfort and control.


